BDBM50319028 (+/-)--4-(5-(amino(4-methoxyphenyl)methyl)-3-methylbenzo[b]thiophen-2-yl)pyrimidin-2-amine::CHEMBL1084795

SMILES COc1ccc(cc1)C(N)c1ccc2sc(c(C)c2c1)-c1ccnc(N)n1

InChI Key InChIKey=WOXPVFLBCQFWPE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319028   

TargetRho-associated protein kinase 1(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319028((+/-)--4-(5-(amino(4-methoxyphenyl)methyl)-3-methy...)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319028((+/-)--4-(5-(amino(4-methoxyphenyl)methyl)-3-methy...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ROCK1 assessed as ATP cunsumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed