BDBM50325425 (S)-(2-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl)(6-fluoropyridin-3-yl)methanone::CHEMBL1222710::N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-{(2S)-1-[(6-fluoropyridin-3-yl)carbonyl]pyrrolidin-2-yl}pyrrolo[2,1-f][1,2,4]triazin-4-amine

SMILES Fc1ccc(cn1)C(=O)N1CCC[C@H]1c1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1

InChI Key InChIKey=XXGADWBTSMHVDF-INIZCTEOSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325425   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50325425((S)-(2-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrr...)
Affinity DataIC50:  162nMAssay Description:Inhibition of IGF1R in IGF1R-SAL cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50325425((S)-(2-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair