BDBM50328440 8-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]-octane::CHEMBL1257336

SMILES Cc1ncoc1-c1nnc(SCCCN2[C@H]3CC[C@@H]2C[C@@H](C3)c2ccc(cc2)C(F)(F)F)n1C

InChI Key InChIKey=UKPYAHVTVCYHSG-FNLKRUPLSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50328440   

TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50328440(8-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50328440(8-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50328440(8-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,...)
Affinity DataIC50:  158nMAssay Description:Displacement of [3H]-dofetilide from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50328440(8-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50328440(8-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50328440(8-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed