BDBM50328603 1-(4-(4-(cyclopropanecarbonyl)piperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one::CHEMBL1256456
SMILES FC(F)(F)c1cc(ccc1N1CCN(CC1)C(=O)C1CC1)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1cnc2ccccc2c1
InChI Key InChIKey=UXERPALKOVLZIM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50328603
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair