BDBM50331835 5-(2-methyl-propylamido)-2-sulfamoyl-1,3,4-thiadiazole::CHEMBL1288807

SMILES CC(C)C(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=DVZGQBMHOJKRPI-UHFFFAOYSA-N

Data  4 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50331835   

TargetCarbonic anhydrase 4(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50331835(5-(2-methyl-propylamido)-2-sulfamoyl-1,3,4-thiadia...)
Affinity DataKi:  0.440nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50331835(5-(2-methyl-propylamido)-2-sulfamoyl-1,3,4-thiadia...)
Affinity DataKi:  0.590nMAssay Description:Inhibition of recombinant human CA2 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCarbonic anhydrase 9(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50331835(5-(2-methyl-propylamido)-2-sulfamoyl-1,3,4-thiadia...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of recombinant human CA9 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50331835(5-(2-methyl-propylamido)-2-sulfamoyl-1,3,4-thiadia...)
Affinity DataKi:  75nMAssay Description:Inhibition of recombinant human CA1 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndochitinase A1(Neosartorya fumigata)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50331835(5-(2-methyl-propylamido)-2-sulfamoyl-1,3,4-thiadia...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Aspergillus fumigatus ChiA1 expressed in Pichia pastoris after 70 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed