BDBM50331935 2-(4-isopentyl-2-oxo-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide::CHEMBL1290212

SMILES CC(C)CCc1c(-c2nccs2)c(=O)[nH]c2ccc(OCC(=O)NC(C)(C)c3ccccc3)cc12

InChI Key InChIKey=SKEXHBJQDVIRIW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331935   

TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331935BDBM50331935(2-(4-isopentyl-2-oxo-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  1.08E+3nMAssay Description:Displacement of [3H]SCH58261 from human adenosine A2A receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331935BDBM50331935(2-(4-isopentyl-2-oxo-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  2.67E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331935BDBM50331935(2-(4-isopentyl-2-oxo-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed