BDBM50336376 (S)-4-(2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)-3,5-difluorobenzoic acid::4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3,5-difluorobenzoic acid::CHEMBL1615154

SMILES OC(=O)c1cc(F)c(NC(=O)[C@H](C2CCCCC2)n2c(nc3cc(F)c(F)cc23)-c2ccc(Cl)cc2)c(F)c1

InChI Key InChIKey=MRVUTCGFXDGVGC-VWLOTQADSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336376   

TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336376((S)-4-(2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at Gal4-fused human FXR by luciferase reporter gene transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336376((S)-4-(2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo...)
Affinity DataIC50:  4nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)