BDBM50341715 3-Amino-6-bromo-N-phenylpyrazine-2-carboxamide::CHEMBL1766761

SMILES Nc1ncc(Br)nc1C(=O)Nc1ccccc1

InChI Key InChIKey=UJCAMIUFQVHBFP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341715   

TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341715BDBM50341715(3-Amino-6-bromo-N-phenylpyrazine-2-carboxamide | C...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of full length recombinant ATR after 24 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341715BDBM50341715(3-Amino-6-bromo-N-phenylpyrazine-2-carboxamide | C...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of full length recombinant ATM after 24 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341715BDBM50341715(3-Amino-6-bromo-N-phenylpyrazine-2-carboxamide | C...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of DNAPK after 2 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed