BDBM50344962 (2S)-2-HYDROXYPENTANEDIOIC ACID::CHEMBL1615211::L-2-Hydroxyglutarate
SMILES O[C@@H](CCC(O)=O)C(O)=O
InChI Key InChIKey=HWXBTNAVRSUOJR-VKHMYHEASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50344962
Affinity DataKi: 8.40E+5nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of KDM2AMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of KDM4CMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of FIH (unknown origin) assessed as hydroxylation of HIF1alphaCAD by MALDI-TOF-MS analysisMore data for this Ligand-Target Pair
TargetProlyl 4-hydroxylase(Paramecium bursaria Chlorella virus 1)
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of KDM4AMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 3.20E+5nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair