BDBM50347329 CHEMBL1796851

SMILES CCN([C@@H]1CCN(C1)C(C)c1ccc(F)cc1)S(=O)(=O)NCCc1c(n[nH]c1-c1cccs1)-c1cnccn1

InChI Key InChIKey=XDQSDBOCBATCPK-AVKWCDSFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347329   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50347329(CHEMBL1796851)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of rabbit 15-LO using linoleic acid by standard colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50347329(CHEMBL1796851)
Affinity DataIC50:  51nMAssay Description:Inhibition of human 15-LO expressed in CHO cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50347329(CHEMBL1796851)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of rabbit 15-LO using arachidonic acid by standard colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed