BDBM50348092 CHEMBL1800273

SMILES Cc1cc(c(cc1-n1[nH]c(cc1=O)C(O)=O)S(O)(=O)=O)S(O)(=O)=O

InChI Key InChIKey=ORRKFRCSPYELFN-UHFFFAOYSA-N

Data  2 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50348092   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataKi:  4.60E+3nMAssay Description:Reversible inhibition at SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataKi:  4.60E+3nMAssay Description:Competitive inhibition at SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of VHXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LMW-PTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50:  1.18E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of SHP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed