BDBM50357731 CHEMBL1915990

SMILES CCCO[C@H]1CN[C@H](C1)[C@@H](O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)[C@H](CCc1ccccc1)N1CC[C@@](CC(C)C)(NC(C)=O)C1=O

InChI Key InChIKey=LPZOLMFQGUDKQH-ZXWXCOCLSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357731   

TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357731(CHEMBL1915990)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing swedish mutant APPMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357731(CHEMBL1915990)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of BACE1 by HPLC methodMore data for this Ligand-Target Pair