BDBM50364373 CHEMBL1950300

SMILES CS(=O)(=O)N[C@H]1CC[C@H](Nc2ncc3nc(Nc4ccc(F)cc4F)n(C4CCOCC4)c3n2)CC1

InChI Key InChIKey=IHQQQWLUGXQOPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364373   

TargetMitogen-activated protein kinase 14(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50364373BDBM50364373(CHEMBL1950300)
Affinity DataIC50: 860nMAssay Description:Inhibition of p38alpha using myelin basic protein as substrate preincubated for 15 mins prior ATP addition measured after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50364373BDBM50364373(CHEMBL1950300)
Affinity DataIC50: 880nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed