BDBM50378960 CHEMBL2011242::US9394290, 5
SMILES Brc1ncccc1Cn1ccnc1
InChI Key InChIKey=YTKQMHFKNFYQRF-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50378960
TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 61nMT: 37°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 911nMT: 37°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 911nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 61nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 61nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 911nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair