BDBM50382271 CHEMBL2022518

SMILES Fc1ccc(cc1)C(NC(=O)CCC(=O)NCC(=O)N1CCC[C@H]1C#N)c1ccc(F)cc1

InChI Key InChIKey=HNYOSYHIRFAFLV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50382271   

TargetProlyl endopeptidase FAP(Mouse)
University of Antwerp (Ua)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382271BDBM50382271(CHEMBL2022518)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382271BDBM50382271(CHEMBL2022518)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant PREP expressed in Escherichia coli assessed as pNA release from Z-Gly-Pro-p-nitroanilide pre-incubated with enzyme fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382271BDBM50382271(CHEMBL2022518)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382271BDBM50382271(CHEMBL2022518)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed