BDBM50382546 CHEMBL2022996

SMILES Cc1cccc(c1)C(CC[C@@H](N)C(O)=O)(c1ccccc1)c1ccccc1

InChI Key InChIKey=JXIGVUPYYZGRRZ-JOCHJYFZSA-N

Data  6 KI  6 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50382546   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataKi:  5.10nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataKi:  6.40nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataKi:  7.10nMAssay Description:Inhibition of MT-stimulated human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain ATPase activity expressed in Escherichia col...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataKi:  10.2nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataKi:  12nMAssay Description:Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataKi:  12.2nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataEC50:  73nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed