BDBM50384653 CHEMBL2037113
SMILES O=C(Nc1ccccc1N1CCNCC1)c1csc(n1)-c1ccc2sccc2c1
InChI Key InChIKey=VWKJPKAJNPLTDF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50384653
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant His-tagged CHK1 using biotin-RSGLYRSPSMPENLNRPR as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Inhibition of CHK1 in human U2OS cells pretreated with hydroxyurea assessed as gamma-H2AX level after 2 hrs by immunofluorescence assayMore data for this Ligand-Target Pair