BDBM50387268 CHEMBL2048571
SMILES CC(C)[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(CC1(C)C)c1ccccc1Cl)C(=O)NCC(C)(C)C(N)=O
InChI Key InChIKey=RBIIKVXVYVANCQ-CUWPLCDZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50387268
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant renin using Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (DABCYL)-Arg as substrate incubated for 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human purified reninMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of renin in cynomolgus monkey plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of renin in cynomolgus monkey plasma after 1 hr by RIAMore data for this Ligand-Target Pair