BDBM50389661 CHEMBL2069800

SMILES Clc1cc(ccn1)-c1nnc(CSc2nnc(-c3ccncc3)n2C2CC2)o1

InChI Key InChIKey=HEACMNRMWPGIPI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50389661   

TargetCytochrome P450 2C19(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389661(CHEMBL2069800)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389661(CHEMBL2069800)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389661(CHEMBL2069800)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 coexpressed in Escherichia coli using phenacetin as probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389661(CHEMBL2069800)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389661(CHEMBL2069800)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389661(CHEMBL2069800)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C8 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed