BDBM50389939 CHEMBL1553629
SMILES CCc1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1
InChI Key InChIKey=AHFZDNYNXFMRFQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50389939
Affinity DataIC50: 853nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55940-induced calcium mobilization incubated fo...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: <1.00E+4nMAssay Description:Antagonist activity at human CB2 receptor expressed in CHO-RD-HGA16 cells overexpressing Galpha16 assessed as inhibition of CP55940-stimulated calciu...More data for this Ligand-Target Pair
Affinity DataEC50: 640nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
Affinity DataEC50: 2.24E+3nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 10 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 1.06E+4nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 10 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Allosteric modulation of human recombinant CB1 receptor expressed in HEK293 cells assessed as stimulation of [3H]CP55940 bindingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Allosteric modulation of human recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of [3H]CP55940 bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 324nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
Affinity DataEC50: 9.10nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
Affinity DataEC50: 83nMAssay Description:Positive allosteric modulator activity at human CB1R expressed in CHO cells assessed as enhanced binding of [3H]CP55,940 after 60 mins by liquid scin...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr...More data for this Ligand-Target Pair
Affinity DataIC50: 853nMAssay Description:Allosteric antagonist activity at human CB1 receptor by Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataIC50: 853nMAssay Description:Allosteric antagonist activity at human CB1 receptor by Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Positive allosteric modulatory activity at C-terminal GFP-tagged human CB1R expressed in HEK293 cell membrane after 90 mins in presence of [3H]CP5594...More data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Allosteric antagonist activity at human CB1 receptor expressed in CHO-RD-HGA16 cells overexpressing Galpha16 assessed as inhibition of CP55940-stimul...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Allosteric antagonist activity at human CB1 receptor expressed in HEK293 cell membrane assessed as inhibition of CP55940-stimulated [35S]GTPgammaS bi...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Allosteric antagonist activity at N-terminal 3HA-tagged human CB1 receptor expressed in HEK293 cells assessed as reduction in CP55940-stimulated inhi...More data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+3nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair