BDBM50396261 CHEMBL2172323

SMILES COC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2ccccc2)nc2ccc(CN3CCCCC3)cc12

InChI Key InChIKey=NFTRTTWPZBZTLY-ZRZAMGCNSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396261   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396261(CHEMBL2172323)
Affinity DataIC50:  54nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396261(CHEMBL2172323)
Affinity DataIC50:  3nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396261(CHEMBL2172323)
Affinity DataIC50:  3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair