BDBM50398847 CHEMBL2177535

SMILES N#Cc1cncc(c1)C1=C[C@@H]2CNC[C@@H](C2)C1

InChI Key InChIKey=DEXLAAAKAUMETM-MNOVXSKESA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50398847   

LigandPNGBDBM50398847(CHEMBL2177535)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]nicotine from human alpha4beta2 nAChR expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398847(CHEMBL2177535)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]nicotine from human alpha4beta2 nAChR expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398847(CHEMBL2177535)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398847(CHEMBL2177535)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398847(CHEMBL2177535)
Affinity DataEC50:  107nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398847(CHEMBL2177535)
Affinity DataEC50:  343nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed