BDBM50399646 CHEMBL2177668::PS210

SMILES OC(=O)C(C(CC(=O)c1ccc(cc1)C(F)(F)F)c1ccccc1)C(O)=O

InChI Key InChIKey=MLJPLHGJBUWCBA-UHFFFAOYSA-N

Data  1 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399646   

TargetSerine/threonine-protein kinase PKH2 [1-944](Candida albicans SC5314)
Universit£Tsklinikum Frankfurt

LigandPNGBDBM50399646(CHEMBL2177668 | PS210)
Affinity DataEC50:  6.00E+4nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen Assay (Perkin Elmer) was performed according to the manufacturer's protocol in 384-well microtiter plates. Incubations were performe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50399646(CHEMBL2177668 | PS210)
Affinity DataEC50:  8.58E+4nMAssay Description:Increase in thermal stability of PDK1 by differential scanning fluorimetryMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50399646(CHEMBL2177668 | PS210)
Affinity DataIC50:  3.90E+4nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen Assay (Perkin Elmer) was performed according to the manufacturer's protocol in 384-well microtiter plates. Incubations were performe...More data for this Ligand-Target Pair