BDBM50399843 CHEMBL2180280

SMILES CC1=C(C(C2C(=O)CC(C)(C)CC2=N1)c1ccc(cc1)-c1ccccc1)C(=O)OCC(F)(F)F

InChI Key InChIKey=YPSPFICMRGWPAL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399843   

TargetTGF-beta receptor type-2(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL

LigandBDBM50399843(CHEMBL2180280)Copy SMILESCopy InChI

Affinity DataIC50:  760nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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