BDBM50401429 CHEMBL2207501

SMILES Cc1nc(CN2CCN(CC2)c2c(Cl)cnc3nc([nH]c23)-c2cn(C)nc2C)no1

InChI Key InChIKey=ZYQKMYRXVHUATB-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401429   

TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401429(CHEMBL2207501)
Affinity DataIC50:  52nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401429(CHEMBL2207501)
Affinity DataKd:  5.60nMAssay Description:Binding affinity to FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401429(CHEMBL2207501)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human ERG by whole-cell voltage clampingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed