BDBM50402165 CHEMBL2207989
SMILES Cc1csc(n1)-c1[nH]c(C)nc1-c1ccc2ncsc2c1
InChI Key InChIKey=OJMAUYGFNZHUQI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50402165
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of ALK5-mediated TNFalpha-induced Smad2/3 phosphorylation in human A549 cells preincubated for 2 hrs before addition of TNFalpha after 1 h...More data for this Ligand-Target Pair