BDBM50417867 CHEBI:69930::CLAUSINE E::Clausine E

SMILES COC(=O)c1cc(O)c2[nH]c3ccccc3c2c1

InChI Key InChIKey=ZWPODTIRGFOENJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50417867   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50417867BDBM50417867(CHEBI:69930 | Clausine E | CLAUSINE E)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of FTO (unknown origin)-mediated demethylation activity using 15-mer ssRNA with CUUGUCA(m6A)CAGCAGA sequence as substrate by reverse phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50417867BDBM50417867(CHEBI:69930 | Clausine E | CLAUSINE E)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of FTO (unknown origin) expressed in Escherichia coli by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50417867BDBM50417867(CHEBI:69930 | Clausine E | CLAUSINE E)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of FTO (unknown origin) expressed in Escherichia coli BL21(DE3) using 5'-TAGACATTGCCATTCTCGATAGG(m6A)-TCCGGTCAAACCTAGACGAATTCCA-3' as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed