BDBM50418001 CHEMBL1672421::US11414402, Example 6

SMILES O=S(=O)(N[C@H]1CCN(C1)C#N)c1ccccc1

InChI Key InChIKey=FXILBKWGQQHVJE-JTQLQIEISA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50418001   

TargetCathepsin B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50418001(CHEMBL1672421 | US11414402, Example 6)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of human recombinant cathepsin B after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50418001(CHEMBL1672421 | US11414402, Example 6)
Affinity DataIC50:  501nMAssay Description:Inhibition of human recombinant cathepsin S after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 30 (USP30)(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM50418001(CHEMBL1672421 | US11414402, Example 6)
Affinity DataIC50:  5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50418001(CHEMBL1672421 | US11414402, Example 6)
Affinity DataIC50:  31.6nMAssay Description:Inhibition of human recombinant cathepsin K after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM50418001(CHEMBL1672421 | US11414402, Example 6)
Affinity DataIC50:  5.50E+4nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50418001(CHEMBL1672421 | US11414402, Example 6)
Affinity DataIC50:  316nMAssay Description:Inhibition of human recombinant cathepsin C after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed