BDBM50418237 CHEMBL1614773

SMILES C[C@@H]1COCCN1c1cc(nc(N)n1)-c1ccc2c(N)[nH]nc2c1

InChI Key InChIKey=WNVXQKKSIHKYCX-SECBINFHSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50418237   

TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418237(CHEMBL1614773)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAurora kinase A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418237(CHEMBL1614773)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418237(CHEMBL1614773)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-phosphoinositide-dependent protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418237(CHEMBL1614773)
Affinity DataIC50:  63nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418237(CHEMBL1614773)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed