BDBM50418578 CHEMBL2029180
SMILES CNS(=C)(=O)c1ccc(Nc2ncc(c(N[C@@H]3CCC[C@H]3N(C)C)n2)C(F)(F)F)cc1
InChI Key InChIKey=OGDXSGNUCLMRSH-LDMUAYPXSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50418578
Affinity DataIC50: 67nMAssay Description:Inhibition of PYK2 assessed as reduction in peptide substrate phosphoryltion by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of PYK2 assessed as reduction in peptide substrate phosphoryltion by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of PYK2 assessed as reduction in peptide substrate phosphoryltion by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of PYK2 by PYK2-LI-COR cellular assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of human ERG by cell based by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of PYK2 by PYK2-LI-COR cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of purified activated FAK kinase domain (410-689) using ATP and Glu and Tyr random peptide polymer substrate by fluorescence polarization ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of purified activated FAK kinase domain (410-689) using ATP and Glu and Tyr random peptide polymer substrate by fluorescence polarization ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of purified activated FAK kinase domain (410-689) using ATP and Glu and Tyr random peptide polymer substrate by fluorescence polarization ...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of PYK2 by PYK2-LI-COR cellular assayMore data for this Ligand-Target Pair