BDBM50418608 CHEMBL1784174
SMILES CC(C)[C@@H](C)NC(=O)c1ccc(nc1)-c1cc(cc(F)c1C)C(=O)NC1CC1
InChI Key InChIKey=KTBQVLJAADKZTA-CQSZACIVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50418608
Affinity DataKi: 7.94nMAssay Description:Inhibition of GST-tagged p38alpha by fluorescence polarization methodMore data for this Ligand-Target Pair
Affinity DataIC50: 19.9nMAssay Description:Inhibition of p38alpha-dependent TNFalpha production in human whole blood preincubated for 1 hr before LPS challenge by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of human CYP2C9 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63.1nMAssay Description:Inhibition of p38alpha-dependent TNFalpha production in human PBMC preincubated for 1 hr before LPS challenge by ELISAMore data for this Ligand-Target Pair