BDBM50420356 NC 150::PHENAZOPYRIDINE HYDROCHLORIDE

SMILES Nc1ccc(\N=N\c2ccccc2)c(N)n1

InChI Key InChIKey=QPFYXYFORQJZEC-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50420356   

TargetReplicase polyprotein 1ab(2019-nCoV)
Chinese Academy of Medical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420356BDBM50420356(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to SARS-CoV-2 nsp12 expressed in Escherichia coli BL21 (DE3) cells using biotinylated EZ-link NHS-LC-LC assessed as dissociation con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Chinese Academy of Medical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420356BDBM50420356(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Affinity DataEC50:  7.37E+3nMAssay Description:Inhibition of his tagged SARS-CoV-2 nsp12 in HEK-293T cells cotransfected with pCoV-GLuc incubated for 24 hrs in the presence of coelenterazine-h by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Chinese Academy of Medical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420356BDBM50420356(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Affinity DataEC50:  8.01E+3nMAssay Description:Inhibition of SARS-CoV-2 nsp14 in HEK-293T cells cotransfected with pCoV-GLuc incubated for 24 hrs in the presence of coelenterazine-h by Gaussia luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSnake venom metalloproteinase BaP1(Terciopelo)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420356BDBM50420356(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Affinity DataIC50: 5.43E+4nMAssay Description:Inhibition of snake venom BaP1 using Abz-Ala-Gly-Leu-Ala-Nba as substrate incubated for 30 mins prior to substrate addition by fluorescence spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNAD(+) hydrolase SARM1(Human)
Umass Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420356BDBM50420356(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Affinity DataKi:  7.00E+4nMAssay Description:Competitive inhibition of recombinant human SARM1 TIR domain (561 to 724 residues) expressed in Escherichia coli C43 (DE3) cells lysates assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD(+) hydrolase SARM1(Human)
Umass Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420356BDBM50420356(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of recombinant human SARM1 TIR domain (561 to 724 residues) expressed in Escherichia coli C43 (DE3) cells lysates using ENAD as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed