BDBM50421415 CHEMBL414948
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[C@@H]2[C@H](O)[C@@H](CO[P@](O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]3n3cnc4c(N)ncnc34)O[C@H]2n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O
InChI Key InChIKey=SIIZPVYVXNXXQG-UQTMIEBXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50421415
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
National Institute Of Diabetes And Digestive Antd Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive Antd Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of the probe bound to Ribonuclease L by compound in radiobinding assay was evaluatedMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
National Institute Of Diabetes And Digestive Antd Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive Antd Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in rabbit reticulocytesMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
National Institute Of Diabetes And Digestive Antd Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive Antd Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in human Daudi lymphoblastoid cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in mouse L cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
National Institute Of Diabetes And Digestive Antd Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive Antd Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 0.210nMAssay Description:Binding affinity of compound to human recombinant Ribonuclease L was evaluatedMore data for this Ligand-Target Pair