BDBM50421683 CHEMBL5283041
SMILES COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCO
InChI Key InChIKey=TTYRLZTWJZCYCC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50421683
TargetSerine/threonine-protein kinase PknB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
William S. Middleton Veterans Hospital
Curated by ChEMBL
William S. Middleton Veterans Hospital
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PknB (1 to 331 residues) expressed in Escherichia coli BL21-Rosetta cells using GarA and ATP as ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PknB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
William S. Middleton Veterans Hospital
Curated by ChEMBL
William S. Middleton Veterans Hospital
Curated by ChEMBL
Affinity DataKd: 340nMAssay Description:Binding affinity to Mycobacterium tuberculosis recombinant N-terminal His-tagged PknB (1 to 331 residues) expressed in Escherichia coli DH5alpha cell...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
William S. Middleton Veterans Hospital
Curated by ChEMBL
William S. Middleton Veterans Hospital
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human Cdk2/Cyclin A using Myelin basic protein as substrate by ATP competitive assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
William S. Middleton Veterans Hospital
Curated by ChEMBL
William S. Middleton Veterans Hospital
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length Pim1 (A15 to K313 residues ) expressed in bacterial expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
William S. Middleton Veterans Hospital
Curated by ChEMBL
William S. Middleton Veterans Hospital
Curated by ChEMBL
Affinity DataKd: 3.00E+3nMAssay Description:Binding affinity to human full length CDK4 (M1 to E303 residues) expressed in mammalian expression system/CyclinD3 by KdELECT kinase assayMore data for this Ligand-Target Pair
Affinity DataKd: 9.30E+3nMAssay Description:Binding affinity to human full length GSK-3 beta (M1 to T433 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Human)
William S. Middleton Veterans Hospital
Curated by ChEMBL
William S. Middleton Veterans Hospital
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length mTOR (L1382 to W2549 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PknB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
William S. Middleton Veterans Hospital
Curated by ChEMBL
William S. Middleton Veterans Hospital
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PknB (1 to 331 residues) expressed in Escherichia coli BL21-Rosetta cells using GarA and ATP as ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PknB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
William S. Middleton Veterans Hospital
Curated by ChEMBL
William S. Middleton Veterans Hospital
Curated by ChEMBL
Affinity DataKd: 180nMAssay Description:Binding affinity to Mycobacterium tuberculosis partial length PknB (M1 to G279 residues) expressed in mammalian expression system by KdELECT kinase a...More data for this Ligand-Target Pair