BDBM50422429 CHEMBL4177131

SMILES Cc1cnc(C)c2nc(nn12)-c1ccn2cc(nc2n1)-c1ccccn1

InChI Key InChIKey=AZFQCTBZOPUVOW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50422429   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50422429(CHEMBL4177131)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ca2+/calmodulin-induced recombinant human full length N-terminal GST-tagged PDE9A2 expressed in baculovirus infected Sf9 cells using cG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50422429(CHEMBL4177131)
Affinity DataIC50:  115nMAssay Description:Inhibition of Ca2+/calmodulin-induced recombinant human full length N-terminal GST-tagged PDE10A1 expressed in baculovirus infected Sf9 cells using c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50422429(CHEMBL4177131)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ca2+/calmodulin-induced full-length recombinant human N-terminal GST-tagged PDE1C expressed in baculovirus infected Sf9 insect cells us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed