BDBM50425121 CHEMBL2313236
SMILES CN1CCN(Cc2ccc3nc(C)c4nnc(-c5ccccc5Cl)n4c3c2)CC1
InChI Key InChIKey=QINZPNYWORORJH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50425121
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag
Curated by ChEMBL
Janssen-Cilag
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of rat PDE10A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen-Cilag
Curated by ChEMBL
Janssen-Cilag
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human recombinant PDE2A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen-Cilag
Curated by ChEMBL
Janssen-Cilag
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair