BDBM50430837 CHEMBL2335154

SMILES Cc1noc(C)c1-c1cc(O)cc(c1)[C@@H](O)c1ccccc1

InChI Key InChIKey=FEQUIPXIENTMJN-SFHVURJKSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50430837   

TargetCREB-binding protein(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50430837(CHEMBL2335154)
Affinity DataIC50:  771nMAssay Description:Binding affinity to CREBBP bromodomain (unknown origin) using H3K56Ac peptide by amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50430837(CHEMBL2335154)
Affinity DataKd:  390nMAssay Description:Binding affinity to human N-His-tagged BRD4 bromodomain 1 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50430837(CHEMBL2335154)
Affinity DataIC50:  382nMAssay Description:Binding affinity to human BRD4 bromodomain 1 using H4Ac4 peptide by amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)