BDBM50431467 CHEMBL2348305

SMILES N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1

InChI Key InChIKey=NKOSKXJRVWVXRI-JTQLQIEISA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50431467   

TargetProliferating cell nuclear antigen(Homo sapiens (Human))
University Of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50431467(CHEMBL2348305)
Affinity DataIC50:  2.00E+4nMAssay Description:Binding affinity to monoubiquitinated PCNA derived from human GM04312 cells assessed as inhibition of interaction with His8-tagged DNA polymerase eta...More data for this Ligand-Target Pair
TargetDNA ligase 1(Homo sapiens (Human))
University Of Allahabad

Curated by ChEMBL
LigandPNGBDBM50431467(CHEMBL2348305)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human DNA ligase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProliferating cell nuclear antigen(Homo sapiens (Human))
University Of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50431467(CHEMBL2348305)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...More data for this Ligand-Target Pair
TargetProliferating cell nuclear antigen(Homo sapiens (Human))
University Of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50431467(CHEMBL2348305)
Affinity DataIC50:  1.00E+3nMAssay Description:Binding affinity to full length human PCNA expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with N-terminal 5-carboxyflu...More data for this Ligand-Target Pair