BDBM50442139 CHEMBL2441273
SMILES CCc1ccc2nc(Nc3cc(Cc4ccccc4)nc(N[C@H]4CC[C@H](O)CC4)n3)sc2c1
InChI Key InChIKey=DPRNXTSMYVCYLJ-XUTJKUGGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50442139
Affinity DataKi: 0.631nMAssay Description:Inhibition of recombinant human FLAG-tagged ITK using biotinylated GST-SAM68 as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Inhibition of Aurora-B (unknown origin) using 5FAM-PKAtide as substrate after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of Btk (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of Tec (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of CAMKK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of Bmx (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of Aurora-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of IR (unknown origin)More data for this Ligand-Target Pair