BDBM50442781 CHEMBL223723

SMILES Fc1ccc(cc1)-n1c2nc(=O)[nH]c(=O)c2cc2cccc(c12)C(F)(F)F

InChI Key InChIKey=IQTPEGHQGLZJNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442781   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50442781(CHEMBL223723)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed