BDBM50450301 CHEMBL4161070
SMILES CNC(=O)[C@@H](NC(=O)c1coc(n1)-c1ccc(CSc2nc3CCCc3c(=O)[nH]2)cc1)C(C)C
InChI Key InChIKey=MSMJXCULHMOGRF-IBGZPJMESA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50450301
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NS0 cells using Knight substrate preincubated for 30 mins followed by substrate addition by f...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human full length MMP13 expressed in mouse NS0 cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Graz University of Technology
Curated by ChEMBL
Graz University of Technology
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP14 expressed in Escherichia coli using fTHP-15 as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Graz University of Technology
Curated by ChEMBL
Graz University of Technology
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP9 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair