BDBM50452368 CHEMBL4215605

SMILES Clc1ccc(CCN2CCN(CC2)c2ccccc2-c2ccccc2)cc1Cl

InChI Key InChIKey=MTJKUJXJFAFMQG-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50452368   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50452368(CHEMBL4215605)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50452368(CHEMBL4215605)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50452368(CHEMBL4215605)
Affinity DataIC50:  840nMAssay Description:Inhibition of SERT in rat brain synaptosomes assessed as reduction in [3H]-5-HT uptake measured after 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed