BDBM50453428 CHEMBL4205098

SMILES [H][C@@]1(C[C@]1([H])c1cccnc1)C(=O)Nc1ccc(CN2C(=O)c3ccccc3C2=O)cc1

InChI Key InChIKey=ZFFWKXDUNGUFER-RTWAWAEBSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453428   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50453428(CHEMBL4205098)
Affinity DataIC50: <1nMAssay Description:Inhibition of full length recombinant human NAMPT using N15-NAM as substrate preincubated for 15 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50453428(CHEMBL4205098)
Affinity DataIC50: <1nMAssay Description:Inhibition of full length recombinant C-terminal His8-tagged human NAMPT using 15N-CONH2Nicotinamide as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB