BDBM50454272 CHEMBL4211084

SMILES COC(=O)c1ccc(NC(=O)CSc2nc3ccccc3n2S(=O)(=O)c2cc(C)cc(C)c2)cc1

InChI Key InChIKey=MYUFPZANAUANOU-UHFFFAOYSA-N

Data  1 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50454272   

TargetReverse transcriptase(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50454272(CHEMBL4211084)
Affinity DataEC50: >8.36E+3nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50454272(CHEMBL4211084)
Affinity DataIC50:  88nMAssay Description:Inhibition of recombinant wild-type HIV-1 3B reverse transcriptase p66/p51 RNA-dependent DNA polymerase activity expressed in Escherichia coli JM109 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50454272(CHEMBL4211084)
Affinity DataEC50:  960nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50454272(CHEMBL4211084)
Affinity DataEC50:  170nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50454272(CHEMBL4211084)
Affinity DataEC50:  160nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50454272(CHEMBL4211084)
Affinity DataEC50: >8.36E+3nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50454272(CHEMBL4211084)
Affinity DataEC50: >8.36E+3nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50454272(CHEMBL4211084)
Affinity DataEC50: >8.36E+3nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed