BDBM50457757 CHEMBL4212375

SMILES CNC(=O)CCNc1cc(nc2cc(OCCCN3CCCC3)c(OC)cc12)-c1ccc(C)o1

InChI Key InChIKey=BAJGTIKDJKXLMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457757   

TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457757(CHEMBL4212375)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457757(CHEMBL4212375)
Affinity DataIC50:  105nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed