BDBM50458669 CHEMBL4215049
SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1cccc(OC(F)(F)F)c1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O
InChI Key InChIKey=IMGYHBFOPYFDNC-IZIIKQMZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50458669
Affinity DataKi: 5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair