BDBM50460069 CHEMBL4228425

SMILES OC[C@@H](O)CONC(=O)c1cc2ccoc2c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=ZIYFSYFDTHXNEB-LLVKDONJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460069   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460069(CHEMBL4228425)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of MEK1 (unknown origin) using Ser/Thr 03 peptide substrate after 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed