BDBM50460740 CHEMBL4228404
SMILES CN(C)c1ccc(cc1)-c1nnc2sc(\C=C\c3ccco3)nn12
InChI Key InChIKey=HYGNBMVDUWDIPJ-MDZDMXLPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50460740
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataKd: 9.30E+3nMAssay Description:Binding affinity to recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance...More data for this Ligand-Target Pair