BDBM50461482 CHEMBL4225299

SMILES CCCCCCCCc1ccc(cc1)-c1ccc2c(c1)nc(N)n(C[C@@H]1CC[C@@H](O1)c1ccccc1)c2=O

InChI Key InChIKey=XDHIEWBZJYZMBU-QCENPCRXSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50461482   

TargetPlasmepsin IV [1-448](Plasmodium falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461482(CHEMBL4225299)
Affinity DataIC50:  110nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461482(CHEMBL4225299)
Affinity DataIC50:  80nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-1 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461482(CHEMBL4225299)
Affinity DataIC50:  400nMAssay Description:Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461482(CHEMBL4225299)
Affinity DataIC50:  88nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed