BDBM50463900 CHEMBL4251258

SMILES Cc1noc(C)c1-c1ccc(=O)n(Cc2ccccc2)c1

InChI Key InChIKey=CIJOVPIWGFQZFF-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463900   

TargetBromodomain-containing protein 4(Human)
Zenith Epigenetics

Curated by ChEMBL
LigandPNGBDBM50463900(CHEMBL4251258)
Affinity DataIC50:  80nMAssay Description:Inhibition of N-terminal His-tagged BRD4 (BD2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-screen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 4(Human)
Zenith Epigenetics

Curated by ChEMBL
LigandPNGBDBM50463900(CHEMBL4251258)
Affinity DataIC50:  280nMAssay Description:Inhibition of N-terminal His-tagged BRD4 (BD1/BD2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-scr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 4(Human)
Zenith Epigenetics

Curated by ChEMBL
LigandPNGBDBM50463900(CHEMBL4251258)
Affinity DataIC50:  230nMAssay Description:Inhibition of N-terminal His-tagged BRD4 (BD1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-screen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)